Alian Aguila ’03, Biological Sciences, Honors College

Alian Aguila

Scientists around the world have trained their microscopes on one strain of bacteria that claims the lives of the elderly and cystic fibrosis patients.

Unraveling how that bacteria develops high levels of resistance against antibiotics is critical to developing effective drugs to fight it.

Recent FIU Honors College graduate Alian Aguila will contribute another piece of the puzzle, the result of two year’s of research in FIU’s Department of Biological Sciences. The research project was recently completed, and Aguila, who finished his B.S. in Biological Sciences in April, has joined the National Institutes of Health (NIH) as a cancer research fellow.

The 24-year-old’s honors and accomplishments are impressive enough— Honors College scholarship recipient and NIH undergraduate fellowship winner. What’s really remarkable, says his major professor Kalai Mathee, are the obstacles Aguila overcame along the way.

Four years ago Aguila and his family lived in their native Cuba and were combating intense government harassment. His mother was under police surveillance and the government took away their home. So in 1998, Aguila abandoned medical school in Havana and fled the country with his mother. He has been supporting his mother throughout his studies, and that has meant working harder than most, Mathee said.

“That’s the thing that really got my attention, he is so focused,’’ Mathee said. “He came here knowing whether he succeeded or not depended on how hard he worked. He had to study twice as hard because he had to maintain all A’s in his classes.”


Pseudomonas aeruginosa
Photo compliments of:
www.cellsalive.com


Early on, Mathee noticed Aguila was always in the lab after hours. His research and research ethics, she said, is equal to that of her graduate students. Under her guidance, he worked in a team with graduate student Kok-Fai Kong to investigate the AmpG protein in the bacteria known as Pseudomonas aeruginosa. Their research maps the structure of the protein, which scientists believe can be targeted for drug treatment.

“This is just a piece of the puzzle,” Aguila said, “but I believe it is significant because no one else has done it before,’’

He said he coped with the frustrations of research by reminding himself that his work can play a role in extending and improving lives. That and soccer. The self-professed soccer nut—Brazil is his team—jokes that he almost failed an exam a couple of years ago because he was so distracted by the World Cup. (Actually, he got a B on the test and an A in the class.)

This summer Aguila spent 10 weeks at the NIH’s National Center for Complementary and Alternative Medicine in Bethesda, MD, after being selected for an internship from among 4,000 applicants. While there, Aguila worked on prostate cancer research. Then, he successfully competed for a two-year cancer research fellowship that began Oct. 1.

Next year, Aguila plans to apply to medical school and is contemplating a specialization in neurology. For now, he is excited to be at NIH where he is working alongside and learning from some of the world’s top scientists.

“Everything that is going on in biomedical research is going on there,’ Aguila said. “It’s very exciting. It’s a good start when you get out of college.”


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